| Date | Location | Result | |
| Nov 20, 2010 | Huntsville, Tex. | Sam Houston 31, Texas State 29 | Box score |
| Nov 13, 2010 | Conway, AR | Sam Houston 20, Central Arkansas 13 | Box score |
| Nov 06, 2010 | Huntsville, Tex. | McNeese 33, Sam Houston 28 | Box score |
| Oct 30, 2010 | Natchitoches, La. | Northwestern State 23, Sam Houston 20 | Box score |
| Oct 23, 2010 | Houston, Texas | Stephen F. Austin 31, Sam Houston 28 | Box score |
| Oct 16, 2010 | Huntsville, Tex. | Sam Houston 57, Southeastern La. 7 | Box score |
| Oct 09, 2010 | Thibodaux, La. | Sam Houston 26, Nicholls 7 | Box score |
| Oct 2, 2010 | Beaumont, Texas | Sam Houston 38, Lamar 10 | Box score |
| Sept 25,2010 | Huntsville, Tex | Sam Houston 30, Gardner-Webb 14 | Box score |
| Sep 18, 2010 | Macomb, Ill. | Western Illinois 56, Sam Houston 14 | Box score |
| Sep 04, 2010 | Waco, Texas | Baylor 34, Sam Houston 3 | Box score |